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[Improved Immunity] New Research Shows Ashwagandha Strengthens Immune System in Healthy Adults

Immune System Modulatory Effects of Ashwagandha Extract

Spoilers for this article

  1. ashwagandha (type of Indian cactus)was found to be effective in strengthening the immune system.
  2. Immunoglobulin and cytokine increases and TBNK cell improvement can prevent infections.
  3. It is expected to be applied to a wide range of infectious disease control measures.

I've been catching colds easily lately,immunityI'd like to up the ante..."

Naturalsupplementindicates certainty, emphasis, etc.immunityIs there anything that can enhance the

I want to know how I can help prevent infections."

This article is for people who are prone to catching colds.

ashwagandha (type of Indian cactus)andimmunityThe latest research has shown that it can help prevent infections by dramatically increasing the

Naturally derivedsupplementbe (formal, literary)ashwagandha (type of Indian cactus)isside effectIt also supports a healthy lifestyle with less worry about

To protect against colds and flu,ashwagandha (type of Indian cactus)is recommended.

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Paper Information

The paper we present here is titled "Withania somnifera (ashwagandha (type of Indian cactus))essenceImmunomodulatory effects of - A randomized, double-blind, placebo-controlled trial and open-label extension in healthy participants(Japanese translation)".

Below is the basic information for this paper.

(data) itemContents
Title.Immunomodulatory Effect of Withania somnifera (Ashwagandha) Extract-A Randomized, Double-Blind, Placebo Controlled Trial with an Open Label Extension on Healthy Participants
author (usu. of a particular book, etc.)Ajit Tharakan, Himanshu Shukla, Irin Rosanna Benny, Matthan Tharakan, Lekha George, Santhosh Koshy
PublicationJ Clin Med
date of issueAugust 18, 2021
Paper Information

What is ashwagandha in the first place?

What is ashwagandha in the first place?

ashwagandha (type of Indian cactus)(scientific name: Withania somnifera Dunal) has been used for thousands of years in Ayurveda, the traditional medicine of India, to treat both physical and mental health problems.stressThe herb has been used as an effective medicine, tonic, and even aphrodisiac.

Nowadays, the effectiveness of these products has been proven by modern science through various clinical studies, and they are attracting attention.

The fruit is an evergreen shrub of the eggplant family. The name comes from the horse's (ashwa) smell (ganda).
Some say it is named after the robust vigor of horses.

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A. Background and Objectives of the Study

In recent years, there has been a growing interest in naturally derived immunostimulants, with particular attention being paid to the effects of botanical ingredients.

In the present study, we investigated the effects of the Indian native plant, Withania somnifera (ashwagandha (type of Indian cactus)TheImpact on immune function in healthy adultsThe purpose of this study is to investigate the

Spoiler,immunityImprovement.

research methods

The following information on this research methodology is provided below.

Research Methods

WSessence=ashwagandha (type of Indian cactus)essenceIt is much easier to read if you remember that

Subjects and study design

The study was a randomized, double-blind, placebo-controlled trial in healthy adults.

Randomized, double-blind, placebo-controlled trial: a long word, but easy to understand when broken down.

randomization

Participants are randomly assigned to experimental and control groups.

double blind trial

Both the subject and the researcher do not know which participant is receiving which treatment.

placebo

Ineffective drug, administered to the control group.

control test

The experimental and control groups will be compared to evaluate the effectiveness of the experimental group.

In summary.Participants are randomly assigned and the results of the experimental and control groups are compared to assess the effectiveness of the treatment. Subjects and researchers do not know who is receiving which treatment.So that's what you mean.

Subjects.ashwagandha (type of Indian cactus)treatment and placebo groups for a 30-day double-blind study, followed by a 30-day open-label period (placebo group was WSessence), a total of 60 days of testing was conducted.

The table is as follows.

(data) itemContents
test designRandomized, double-blind, placebo-controlled trial
subject (of taxation, etc.)Healthy adults
test (testing) periodTotal 60 days (30-day double-blind study period + 30-day open-label extension period)
Grouping of subjectsashwagandha (type of Indian cactus)essence(WS)essence(1) group (2) group (3) group (4) group (5) group (6) placebo group (7)
WSessencedosage60 mg per day
placeboIt looks and tastes the same,ashwagandha (type of Indian cactus)essenceInvalid drug not containing
Change of extension periodPlacebo group subjects WS during open label extension period (30 days)essenceswitched to
Subjects and study design

Personally, I think that the placebo group also has the ability to laterashwagandha (type of Indian cactus)The interesting part is to switch to

Administration of WS extract and placebo

WSessenceThe treatment group was given 60 mg per day ofashwagandha (type of Indian cactus)were administered, while the placebo group received a similarly visible, ineffective drug.

In the open label period, the placebo group also received 60 mg per day ofashwagandha (type of Indian cactus)was administered.

(data) itemContents
WSessencedosage group60 mg per day.ashwagandha (type of Indian cactus)essenceprescribing medicine
Placebo groupIt looks and tastes the same,ashwagandha (type of Indian cactus)essenceInvalid drug administration not including
Open Label Extension PeriodSubjects in the placebo group also received 60 mg per day ofashwagandha (type of Indian cactus)essenceis administered
WSessenceand placebo administration

Open label extension period = the additional period reported in the previous section.

Outcome Measurement Indicators

Outcome measurement indicators: in short,Objective measurement and evaluation with numerical expression of results evaluated in researchThe first thing to do is to

In this study, the following immune-related indices were measuredashwagandha (type of Indian cactus)essenceWe evaluated the immunomodulatory effects of

  1. Immunoglobulins (IgA, IgM, IgG, IgG2, IgG3, IgG4)
  2. Cytokines (IFN-γ, IL-4)
  3. TBNK cells (CD45+, CD3+, CD4+, CD8+, CD19+, NK cells)
immunoglobulin

A protein that plays an important role in the body's immune system, protecting against infections and pathogens.

cytokine

Proteins responsible for cell-to-cell communication within the immune system.

Regulates cell growth, activation, and migration during infection and inflammation.

TBNK cell

Key cells of the immune system. Protects against infection and disease.

Below is a brief description of the major types of TBNK cells.

  1. T cells: destroy virus-infected cells and cancer cells.
  2. Helper T cells: regulate immune response
  3. Killer T cells: attack infected cells.
  4. B cells: produce antibodies and fight infection.
  5. NK cells: Naturally killing cells attack virally infected cells and cancer cells.

These measures were measured prior to study entry, at the end of the double-blind study period (30 days later), and at the end of the open-label extension period (60 days later).

measurement indexDetailsMeasuring period
immunoglobulinIgA, IgM, IgG, IgG2, IgG3, IgG4Before the start of the study, after the end of the double-blind study period (after 30 days), and after the end of the open-label extension period (after 60 days)
cytokineIFN-γ, IL-4Before the start of the study, after the end of the double-blind study period (after 30 days), and after the end of the open-label extension period (after 60 days)
TBNK cellCD45+, CD3+, CD4+, CD8+, CD19+, NK cellsBefore the start of the study, after the end of the double-blind study period (after 30 days), and after the end of the open-label extension period (after 60 days)
Outcome Measurement Indicators

ashwagandha (type of Indian cactus)What has happened to these three due to the administration is,immunitySo it is an indication of improvement.

findings

Results of a 30-day double-blind study period

After the 30-day double-blind study period, WSessenceimmunoglobulins, cytokines, and TBNK cells in the treatment group.Significantly increased(p < 0.05).

In contrast, TBNK cells were significantly reduced (p < 0.05) in the placebo group, and immunoglobulins and cytokines wereThere was no change.(p > 0.05).

Open Label Extension Period Results

On the 60th day of the open label extension period,WS from placebo groupessenceSubjects switched to significantly increased immunoglobulins, cytokines, TBNK cells(p < 0.05).

In addition, WSessenceSubjects who remained in the treatment group also showed a significant increase in these indices inFurther significant improvement(p < 0.05) was found.

ashwagandha (type of Indian cactus)The placebo group that switched to the placebo group improved.

originallyashwagandha (type of Indian cactus)So the pairs that were have improved even more.

Adverse Effects Reported

reported in this study.side effectThere were no

ashwagandha (type of Indian cactus)essencewas effective in improving the immune profile of healthy adults, suggesting that it may enhance the congenital and acquired immune system in people at risk of infection and in widespread infections.

What to consider

Immunomodulatory effects of ashwagandha extract

The results of this study are,ashwagandha (type of Indian cactus)essence(WS)essence) has been shown to be effective in improving the immune profile of healthy adults.

In particular, immune-related indices such as immunoglobulins, cytokines, and TBNK cells were significantly increased.

This is a WSessencehas the ability to modulate the innate and acquired immune system.

In fact, themanagerbe beyond one's controlashwagandha (type of Indian cactus)and I haven't had a cold except for Corona for over 4 years. I could not escape Corona.

Applications for Prevention of Infectious Diseases and Immune System Enhancement

ashwagandha (type of Indian cactus)essenceThe immunomodulatory effects of,Potential applications in preventing infectious diseases and strengthening the immune systemThere are

Especially in the contemporary context of high risk of coronary infection, WSessenceThe immune system is expected to be strengthened through the use of

Especially in the contemporary context of high risk of coronary infection, WSessenceThe immune system is expected to be strengthened through the use of

This reduces the risk of developing infectious diseases and maintaining good health.

Having said that, as mentioned above,managertook for the corona.

However, it was not serious and was only a minor illness.

Summary: Ashwagandha improves immunity.

How was it? I would like to conclude by summarizing the contents of this article.

Spoilers for this article

  1. ashwagandha (type of Indian cactus)was found to be effective in strengthening the immune system.
  2. Immunoglobulin and cytokine increases and TBNK cell improvement can prevent infections.
  3. It is expected to be applied to a wide range of infectious disease control measures.

In this study,ashwagandha (type of Indian cactus)essenceimproved immune profiles and enhanced immune responses.

ashwagandha (type of Indian cactus)essenceis promising as a countermeasure for people at high risk of infection and for a wide range of infectious diseases, and if future research confirms its effectiveness, it could be used to prevent infectious diseases andimmunityIt could be used as a means of improving

Those who catch cold easily,immunityIf you care about improving theashwagandha (type of Indian cactus)Consider taking a

That's all for this article. Thank you for reading to the end. See you soon.

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Immune System Modulatory Effects of Ashwagandha Extract

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